Metabolic and histopathological consequences of a fatty liver during the acute stages of myocardial infarction in rats.

  • 1 October 1971
    • journal article
    • Vol. 52  (5) , 565-82
Abstract
Adult, male Sprague-Dawley rats were fed a regular rat chow diet or a diet containing 1 per cent orotic acid. Ten days later, orotic acid fed animals had severe, fatty metamorphosis of the liver. Both the regular diet animals and the orotic acid fed animals were given 2, daily, s.c. injections of isoproterenol (50 mg./100 g. b.w.) in order to induce severe myocardial infarction.