Alkaline phosphatase levels in osteosarcoma tissue are related to prognosis
Open Access
- 1 December 1979
- Vol. 44 (6) , 2291-2293
- https://doi.org/10.1002/1097-0142(197912)44:6<2291::aid-cncr2820440643>3.0.co;2-s
Abstract
Levels of alkaline phosphatase were measured in the primary tumor of 26 patients with osteosarcoma. One of seven patients with a tissue alkaline phosphatase level less than 0.6 μM/min/mg developed pulmonary metastases. In contrast, 16 of 17 patients with a tissue alkaline phosphatase level greater than 0.6 μM/min/mg developed pulmonary metastases. It thus appears that tissue alkaline phosphatase levels of primary osteosarcomas are strongly correlated with prognosis (p < .01).This publication has 18 references indexed in Scilit:
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