Decreases of CD4‐ and CD8‐positive T lymphocytes in retired chromate workers
- 1 June 1995
- journal article
- research article
- Published by Wiley in American Journal of Industrial Medicine
- Vol. 27 (6) , 877-882
- https://doi.org/10.1002/ajim.4700270611
Abstract
To investigate the effects of chromates on the human immune system, we measured total T lymphocytes and their two major subpopulations (CD4 + and CD8 + T lymphocytes) in the peripheral blood of 19 retired male workers who had been exposed to chromate at a chemical plant. The results indicated that both CD4 + and CD8 + T lymphocytes were significantly decreased, resulting in decreases in total T lymphocytes and total lymphocytes.Keywords
This publication has 11 references indexed in Scilit:
- Decrease of CD4-positive T Lymphocytes in Workers Exposed to Benzidine and Beta-naphthylamineArchives of environmental health, 1993
- One hundred years of chromium and cancer: A review of epidemiological evidence and selected case reportsAmerican Journal of Industrial Medicine, 1990
- Altered immune status in aluminum reduction plant workersAmerican Journal of Industrial Medicine, 1990
- A novel epitope of the LFA-1 antigen which can distinguish killer effector and suppressor cells in human CD8 cellsNature, 1987
- Lymphocyte Subsets in Lung CancerChest, 1987
- The isolation and characterization of the human suppressor inducer T cell subset.The Journal of Immunology, 1985
- Characterization of a phenotypically distinct subpopulation of Leu-2+ cells that suppresses T cell proliferative responses.The Journal of Immunology, 1983
- Subpopulations of human natural killer cells defined by expression of the Leu-7 (HNK-1) and Leu-11 (NK-15) antigens.The Journal of Immunology, 1983
- Monoclonal Antibodies Defining Distinctive Human T Cell Surface AntigensScience, 1979
- Separation of functional subsets of human T cells by a monoclonal antibody.Proceedings of the National Academy of Sciences, 1979