The virulence plasmid of Salmonella dublin: detailed restriction map and analysis by transposon mutagenesis
- 1 June 1990
- journal article
- research article
- Published by Microbiology Society in Journal of General Microbiology
- Vol. 136 (6) , 1117-1123
- https://doi.org/10.1099/00221287-136-6-1117
Abstract
A detailed restriction map of the virulence plasmid of Salmonella dublin has been determined and used for comparison with the virulence plasmid from S. typhimurium. Two regions were identified which appeared to be similar based on blotting and restriction data. One, of about 22 kb, encompassed the virulence region; the other, of about 8 kb, was outside it. The locations of 259 transposon insertions on the S. dublin plasmid were determined and related to their effect on virulence. One gene involved in virulence but outside the essential virulence region was shown to affect citrate metabolism.Keywords
This publication has 16 references indexed in Scilit:
- Physical and genetic mapping of the Salmonella dublin virulence plasmid pSDL2. Relationship to plasmids from other Salmonella strains.Journal of Clinical Investigation, 1988
- A Common Virulence Region on Plasmids from Eleven Serotypes of SalmonellaMicrobiology, 1988
- Evidence of correlation between 50-kilobase plasmid of Salmonella choleraesuis and its virulenceMicrobial Pathogenesis, 1988
- A new method for the physical and genetic mapping of large plasmids: application to the localisation of the virulence determinants on the 90 kb plasmid of Salmonella typhimuriumMicrobial Pathogenesis, 1987
- Contribution of Salmonella gallinarum large plasmid toward virulence in fowl typhoidInfection and Immunity, 1987
- Virulence associated plasmids of Salmonella serotype typhimurium in experimental murine infectionAnnales de l'Institut Pasteur / Microbiologie, 1986
- The role of plasmid genes in the pathogenicity of Salmonella dublinJournal of Medical Microbiology, 1986
- Evidence for Related Virulence Sequences in Plasmids of Salmonella dublin and Salmonella typhimuriumMicrobiology, 1985
- Epidemiology of virulence-associated plasmids and outer membrane protein patterns within seven common Salmonella serotypesInfection and Immunity, 1985
- Association of adhesive, invasive, and virulent phenotypes of Salmonella typhimurium with autonomous 60-megadalton plasmidsInfection and Immunity, 1982