Angiogenesis Inhibition and Choroidal Neovascularization Suppression by Sustained Delivery of an Integrin Antagonist, EMD478761
- 1 November 2007
- journal article
- Published by Association for Research in Vision and Ophthalmology (ARVO) in Investigative Opthalmology & Visual Science
- Vol. 48 (11) , 5184-5190
- https://doi.org/10.1167/iovs.07-0469
Abstract
Purpose. To evaluate the angiogenic inhibitory effects of an αvβ3/αvβ5 integrin antagonist, EMD478761, released from a polymeric implant in a chick chorioallantoic membrane (CAM) assay and laser-induced experimental choroidal neovascularization (CNV) in rats.Keywords
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