The Hematologic, Gastric Acidity and Cerebrospinal Fluid Findings in Multiple Sclerosis

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Abstract
The laboratory findings of 80 unselected cases of multiple sclerosis, assembled from the records of the Montreal Neurological Inst., were analyzed for the blood picture, C. S. F. findings, and gastric acidity. Only minor abnormalities were found in the hemogram, bleeding time, clotting time, serum bilirubin, and Rumpel-Leede test, and these could not have been correlated with the clinical picture of the disease. The incidence of achlorhydria was not higher than among normal controls. 64% of all C. S. F. samples examined showed abnormalities in 1 or more of the following total protein, cell count or colloidal Au reaction. This has been held to be helpful in differential diagnosis between multiple sclerosis and other C. N. S. diseases. No correlation between C. S. F. changes and the acuteness of disseminated sclerosis could be found.

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