Triiodothyronine accelerates the synthesis of Synapsin I in developing neurons from fetal rat brain cultured in a synthetic medium
- 1 August 1990
- journal article
- research article
- Published by Springer Nature in Neurochemical Research
- Vol. 15 (8) , 827-831
- https://doi.org/10.1007/bf00968561
Abstract
The effect of Triiodothyronine (T3) on Synapsin I appearance in rat cortical neurons has been investigated in vitro. Neuronal cultures from 16-day-old fetal rat brain grown in the absence of T3, express immunohystochemically detectable Synapsin I at the 14th day in vitro. The addition of the hormone to the culture medium determines an early (at the 7th day in vitro) appearance of fluorescent dots specific for Synapsin I.Keywords
This publication has 15 references indexed in Scilit:
- Multiple synapsin I messenger RNAs are differentially regulated during neuronal development.The Journal of cell biology, 1988
- Triiodothyronine (T3) induces neurite formation and increases synthesis of a protein related to MAP 1B in cultured cells of neuronal originDevelopmental Brain Research, 1988
- Cellular mechanism of action of thyroid hormonesDifferentiation, 1987
- Triiodothyronine‐Induced Shortening of Chromatin Repeat Length in Neurons Cultured in a Chemically Denned MediumJournal of Neurochemistry, 1987
- Synapsin I: A synaptic vesicle-associated neuronal phosphoproteinBiochemical Pharmacology, 1986
- Formulation of a novel synthetic medium for selectively culturing rat CNS neuronsDevelopmental Brain Research, 1985
- Triiodothyronine enhances the morphological maturation of dopaminergic neurons from fetal mouse hypothalamus cultured in serum-free mediumNeuroscience, 1983
- Stimulation of tubulin synthesis by thyroid hormone in the developing rat brainBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1983
- Synapsin I (protein I), a nerve terminal-specific phosphoprotein. I. Its general distribution in synapses of the central and peripheral nervous system demonstrated by immunofluorescence in frozen and plastic sections.The Journal of cell biology, 1983
- Triiodothyronine enhancement of neuronal differentiation in aggregating fetal rat brain cells cultured in a chemically defined mediumBrain Research, 1980