Early Treatment for HIV

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Abstract
Serologic testing for the human immunodeficiency virus (HIV) has shown that millions of persons are infected worldwide. What proportion of these will have progression to symptomatic and indeed fatal disease, and at what rate, are critical questions.Meticulous studies of the virologic features and natural history of HIV infection are now providing answers and a grim vision of the future. Viral replication can be detected even while infection appears to be clinically quiescent, and it increases enormously as clinical disease approaches.1 In approximately half the persons infected with HIV, the acquired immunodeficiency syndrome (AIDS) develops within a 10-year period.2 Although . . .