PAIN ON INJECTION OF PROPOFOL: COMPARISON OF LIGNOCAINE WITH METOCLOPRAMIDE
Open Access
- 1 September 1992
- journal article
- clinical trial
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 69 (3) , 316-317
- https://doi.org/10.1093/bja/69.3.316
Abstract
We have conducted a randomized, double-blind study in 255 ASA I and II patients to compare the efficacy of lignocaine and metoclopramide in minimizing the pain of injection of i. v. propofol. When administered immediately before propofol into a dorsal hand vein, compared with placebo both drugs significantly reduced the incidence of pain on subsequent injection of propofol (P < 0.007). Twenty patients who had received metoclopramide (n = 85) experienced pain, compared with 18 who had received lignocaine (n = 85) and 42 who had been pretreated with saline (n = 85).Keywords
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