IDENTIFICATION AND CHARACTERIZATION OF A CIRCULATING TUMOR-ASSOCIATED ONCOFETAL PROTEIN FROM A RADIATION-INDUCED ADENOCARCINOMA OF RAT SMALL BOWEL

  • 1 January 1976
    • journal article
    • research article
    • Vol. 36  (9) , 3260-3264
Abstract
A tumor associated protein from the cellular membranes of a radiation induced rat small bowel adenocarcinoma was identified, found to be serologically unaltered in the circulatory system and was susceptible to acid hydrolysis. The immunochemical reactivity was unchanged by heat, alkali or neuraminidase digestion. The protein appeared to be a single immunologically active species, but it was structurally composed of a heterogeneous group of proteins.

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