Deflectins, new antimicrobial azaphilones from Aspergillus deflectus.
- 1 January 1981
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 34 (8) , 923-928
- https://doi.org/10.7164/antibiotics.34.923
Abstract
Five structurally related, angular azaphilones, the deflectins, were isolated from the mycelia of A. deflectus. The structures of all compounds were established. Besides the inhibitory effects on the growth of bacteria and fungi, these compounds showed lytic activity towards bacteria and erythrocytes and cytotoxic activity towards cells of the ascitic form of Ehrlich carcinoma of mice. The inhibitory effects of the deflectins could be reversed by the addition of serum or serum albumin.This publication has 3 references indexed in Scilit:
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- Metabolic products of microorganisms. 163. Desferritriacetylfusigen, an antibiotic from Aspergillus deflectus.The Journal of Antibiotics, 1976
- The structure of dihydrodeoxy-8-epi-austdiol and the absolute configuration of the azaphilonesJournal of the Chemical Society, Perkin Transactions 1, 1976