Q-FEVER HEPATITIS - CLINICAL MANIFESTATIONS AND PATHOLOGICAL FINDINGS

  • 1 January 1982
    • journal article
    • research article
    • Vol. 83  (2) , 474-479
Abstract
The clinical manifestations and pathological findings in 5 patients with serologically diagnosed acute Q fever are reported. Each patient presented with headache, malaise, spiking fever and hepatitis. Percutaneous biopsy of the liver in 4 patients revealed granulomatous changes with many lesions containing a dense fibrin ring surrounding a central lipid vacuole. Biopsy of the bone marrow in the 5th patient revealed similar abnormalities. These lipogranulomas should be considered characteristic of Q fever.

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