Response of Epididymal Adipose Tissue to Small Concentrations of Insulin: Effect of Cortisone.

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Abstract
Rat epididymal adipose tissue was incubated at 37[degree]C in Krebs-Hanseleit bicarbonate solution containing 200 mg% each of glucose and gelatin. The stimulation of glucose uptake or CO2 evolution produced by 20, 50, or 104 / uuunits insulin per ml in vitro was markedly reduced by prior subcutaneous injection of the rat tissue donor with 7 mg cortisone acetate in divided doses over a period of 3 1/2 days.