Improved and Extended One-Step Conversion of Primary Amines into Nitriles by Copper-Catalyzed Oxidation
- 1 January 1989
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1989 (06) , 453-454
- https://doi.org/10.1055/s-1989-27286
Abstract
An improved and extended methodology for Kametani's oxidation of primary amines to nitriles by the [CU(I)Cl/O2/pyridine] system is reported. By this procedure aliphatic or aromatic nitriles are obtained in almost quantitative yields with very high purity.Keywords
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