CHILDREN OF FEMALE RENAL TRANSPLANT RECIPIENTS

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Abstract
Results of a follow-up of 5 children, aged 4.5-9 yr, who were born to kidney transplanted mothers are presented. Various immunological parameters were within normal limits with the possible exception of 1 child who exhibited a granulocytopenia which normalized at .apprx. 5 yr of age. Three children whose mothers were [hepatitis B surface antigen] carriers during and after pregnancy have become antigen carriers and show slightly elevated levels of liver transferases. One child has a cardiac anomaly and signs of slight neurological dysfunction. In other respects the children are well and show normal psychomotor and somatic development. The rather sparse information from the literature regarding this group of children indicates a surprisingly low frequency of severe physical complications.