Synthesis of 1, 2‐Bis(N‐Substituted β‐Aspartyl) Hydrazines as Potential Hypocholesteremics
- 1 September 1974
- journal article
- research article
- Published by Wiley in Journal of the Chinese Chemical Society
- Vol. 21 (3) , 157-162
- https://doi.org/10.1002/jccs.197400021
Abstract
Addition of two equivalent amounts of appropriate primary amine to the carbon‐carbon double bonds of 1, 2‐dimaleic acid hydrazine(I) in suitable solvents at room temperature of under reflux provided a number of 1, 2‐bis(N‐substituted β‐aspartyl) hydrazines (IIa‐k) in satisfactory yields. In some cases of this reaction, the mono‐aminated intermediates (IIIa‐c) were also isolated.Keywords
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