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Improved Cycle Sequencing of GC-Rich Templates by a Combination of Nucleotide Analogs
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Improved Cycle Sequencing of GC-Rich Templates by a Combination of Nucleotide Analogs
Improved Cycle Sequencing of GC-Rich Templates by a Combination of Nucleotide Analogs
Michael Motz
Michael Motz
SP
Svante Pääbo
Svante Pääbo
CK
Christian Kilger
Christian Kilger
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29 August 2000
journal article
Published by
Taylor & Francis
in
BioTechniques
Vol. 29
(2)
,
268-270
https://doi.org/10.2144/00292st01
Abstract
A common problem in automated DNA sequencing when applying the Sanger chain termination method is ambiguous base calling caused by band compressions. Band compressions are caused by anomalies in th...
Keywords
BEHAVIOR
OPTIMAL
DNA FRAGMENTS
NUCLEOTIDE ANALOGS
DGTP
DITP
DEAZA
BAND COMPRESSIONS
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