SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
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Open Access
- 1 May 2002
- journal article
- review article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 109 (9) , 1125-1131
- https://doi.org/10.1172/jci15593
Abstract
No abstract availableKeywords
This publication has 47 references indexed in Scilit:
- Endoplasmic reticulum localization of the low density lipoprotein receptor mediates presecretory degradation of apolipoprotein BProceedings of the National Academy of Sciences, 2002
- Diminished Hepatic Response to Fasting/Refeeding and Liver X Receptor Agonists in Mice with Selective Deficiency of Sterol Regulatory Element-binding Protein-1cJournal of Biological Chemistry, 2002
- Mutant Mammalian Cells as Tools to Delineate the Sterol Regulatory Element-Binding Protein Pathway for Feedback Regulation of Lipid SynthesisArchives of Biochemistry and Biophysics, 2002
- Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene.Journal of Clinical Investigation, 1997
- The SREBP Pathway: Regulation of Cholesterol Metabolism by Proteolysis of a Membrane-Bound Transcription FactorCell, 1997
- Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells.Journal of Clinical Investigation, 1997
- Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells.Journal of Clinical Investigation, 1997
- Sterol Resistance in CHO Cells Traced to Point Mutation in SREBP Cleavage–Activating ProteinCell, 1996
- Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a.Journal of Clinical Investigation, 1996
- Sterol-dependent Transcriptional Regulation of Sterol Regulatory Element-binding Protein-2Journal of Biological Chemistry, 1996