A FACILE SYNTHESIS OF α-C-RIBOFURANOSIDES FROM 1-O-ACETYL RIBOSE IN THE PRESENCE OF TRITYL PERCHLOLATE

Abstract
In the presence of a catalytic amount of trityl perchlorate, 1-O-acetyl ribose stereoselectively reacts with silylated nucleophiles, such as silyl enol ether, allylsilane, and trimethylsilyl cyanide, to give the corresponding α-C-ribofuranosides in excellent yields.