Gene for Neuraminidase Activity on Mouse Chromosome 17 Near H-2: Pleiotropic Effects on Multiple Hydrolases
- 3 April 1981
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 212 (4490) , 63-65
- https://doi.org/10.1126/science.7209520
Abstract
The low activity of liver neuraminidase that is characteristic of mouse strain SM/J is inherited as a single gene on chromosome 17, near the major histocompatibility complex. This gene, neuraminidase-1 ( Neu-1 ), is represented by the low activity allele Neu-1 s in SM/J and the high activity allele Neu-1 b in C57BL/6J and most other strains. Previously described variations in the posttranslational processing of acid phosphatase, α-mannosidase, arylsulfatase-B, and α-glucosidase are attributed to pleiotropic effects of this gene.This publication has 16 references indexed in Scilit:
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