Coumarin Anticoagulant Therapy of Patients with T-Tube Drainage of the Common Bile Duct

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Abstract
THE value of coumarin anticoagulant therapy in both the prevention and the treatment of postoperative thromboembolic disease is well established.1 Patients who have external (T-tube) drainage of the common bile duct present a risk, theoretically at least, of bleeding associated with the use of coumarin anticoagulant therapy. The presence of a drainage tube sometimes aggravates bleeding, but perhaps even more important in these patients is the external drainage of bile. It has been amply demonstrated that the presence of bile salts in the gastrointestinal tract is necessary for the absorption of natural vitamin K, and it is also well recognized . . .