Amino acid sequence elucidation of human acrosin‐trypsin inhibitor (HUSI‐II) reveals that Kazal‐type proteinase inhibitors are structurally related to β‐subunits of glycoprotein hormones
- 17 September 1990
- journal article
- Published by Wiley in FEBS Letters
- Vol. 270 (1-2) , 222-224
- https://doi.org/10.1016/0014-5793(90)81273-q
Abstract
The amino acid sequence of the acrosin-trypsin inhibitor HUSI-II from human seminal plasma is presented which unequivocally identifies HUSI-II as being of Kazal-type. In addition, the HUSI-II sequence shows a striking similarity to the middle part of glycoprotein hormone β-subunits thus revealing a hitherto unknown structural and evolutionary relationship between Kazal-type inhibitors and glycoprotein hormones.Keywords
This publication has 21 references indexed in Scilit:
- On the size of the active site in proteases. I. PapainPublished by Elsevier ,2005
- Molecular cloning and nucleotide sequence of human pancreatic secretory trypsin inhibitor (PSTI) cDNABiochemical and Biophysical Research Communications, 1985
- Homologies in the Structures of Bull Seminal Plasma Acrosin Inhibitors and Comparison with other Homologous Proteinase Inhibitors of the Kazal TypeHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1983
- Amino acid sequence of the acidic acrosin inhibitor (BUSI I B2) from bull seminal plasmaCollection of Czechoslovak Chemical Communications, 1983
- Three-dimensional structure of the complex between pancreatic secretory trypsin inhibitor (Kazal type) and trypsinogen at 1.8 Å resolutionJournal of Molecular Biology, 1982
- Crystallographic refinement of Japanese quail ovomucoid, a Kazal-type inhibitor, and model building studies of complexes with serine proteasesJournal of Molecular Biology, 1982
- Protein Inhibitors of ProteinasesAnnual Review of Biochemistry, 1980
- A technique for the removal of pyroglutamic acid from the amino terminus of proteins using calf liver pyroglutamate amino peptidaseBiochemical and Biophysical Research Communications, 1978
- KURZMITTEILUNGHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1971
- Isolation of a Crystalline Trypsin Inhibitor-Anticoagulant Protein from Pancreas1aJournal of the American Chemical Society, 1948