The Use of the Protou Magnetic Pesonance (PMR) Spectroscopy in the Quantitative Determination of Dapsone in the Bulk and Tablets

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Abstract
A quantitative procedure for the determination of dapsone [80-08-0], I, in authentic mixtures and tablets, II, has been developed using the PMR spectroscopy. The comparison of the proposed PMR method with the official assays of the B.P. 1980 was achieved, and the results were statistically evaluated. The PMR determination is fairly accurate, more precise and providing advantageous traits regarding the simplicity and the rapidity of the method as well as the specificity of the technique in identifying and testing the purity of the compound.