DELETION SHORT ARM 18 AND SILVER‐RUSSELL SYNDROME

Abstract
A 14 yr old boy presented with physical signs of the Silver-Russell syndrome. He also had low-set, large protruding ears, ptosis, broad nasal base, thick protruding lips, pronounced caries, malignment of teeth, micrognathia and mental retardation. Chromosome examination showed deletion of the short arms of chromosome No. 18. Considering the previous findings of chromosome No. 18 aberrations in some patients with Silver-Russell syndrome such patients should always have chromosome examination made.