Chromosomal localization of human leukocyte, fibroblast, and immune interferon genes by means of in situ hybridization
- 1 December 1982
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 79 (24) , 7809-7813
- https://doi.org/10.1073/pnas.79.24.7809
Abstract
Recombinant plasmids containing cDNA inserts from human leukocyte interferon (IFN-α), fibroblast interferon (IFN-β), or immune interferon (INF-γ) genes were radiolabeled and hybridized in situ to human metaphase chromosome preparations. The results localized the human IFN-α and IFN-β genes to the short arm of chromosome 9(p21→pter) and localized the IFN-γ gene to the long arm of chromosome 12(q24.1).Keywords
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