MONOCLONAL-ANTIBODIES TO HUMAN SYNCYTIOTROPHOBLAST
- 1 January 1981
- journal article
- research article
- Vol. 43 (3) , 541-546
Abstract
Two [mouse] monoclonal antibodies, NDOG1 and NDOG2, were produced which are directed towards human syncytiotrophoblast. The antigens detected by these antibodies are absent from adult human liver, heart, kidney, brain and from normal human sera. The NDOG1 antigen but not NDOG2 antigen is a component of pregnancy sera and falls to undetectable levels within 6 h of placental delivery. This molecule is not human chorionic gonadotrophin, human placental lactogen, placental alkaline phosphatase, SP1 or PAPP-A. Immunoperoxidase staining shows that both antigens are on apical aspects of the syncytiotrophoblast and not in the villous stroma.This publication has 21 references indexed in Scilit:
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