Natural Course of Severe Acute Respiratory Syndrome–Associated Coronavirus Immunoglobulin after Infection
Open Access
- 1 November 2004
- journal article
- Published by Oxford University Press (OUP) in The Journal of Infectious Diseases
- Vol. 190 (9) , 1706-1707
- https://doi.org/10.1086/424573
Abstract
To the Editor—In Chen et al.'s recent study, severe acute respiratory syndrome (SARS)-associated coronavirus (SARSCoV) IgG was shown to be persistent for up to 60 days [ 1]. Their results suggested that production of this antibody is dependent on CD4+ cells and might play a role in protective immunity against SARS CoV. On the other hand, IgM has been found to decrease and become undetectable 11 weeks into the recovery phase [ 2]. Whether survivors of SARS can have persistent antibody and lifelong immunity against SARS CoV is unknown.Keywords
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