New reactions for use in natural products chemistry

Abstract
Radicals, generated from isopropylidene uronic esters of N-hydroxy-2-thiopyridone, add readily to electron-poor alkenes in a stereospecific fashion, leading to functionalised chain-elongated furanosides and D-ribo-nucleosides through carbon-4. The directive effect of the ketal group in controlling the newly created chirality is noteworthy.

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