BONE-MARROW EOSINOPHILIA IN THE MOUSE.

Abstract
The number of eosinophil leukocytes in the bone marrow of untreated mice (Cpb:SE) varies widely. Analysis of variance of eosinophils/1000 cells in 165 mice over a 35 day period showed that the results were consistent with the assumption that there are no changes during this interval (P > 0.05). The number of eosinophils/1000 cells found in the various groups are not directly comparable; the mean number for the 4 groups investigated at intervals of about 3 mo. differed by a factor of up to 3. On the basis of the variability found, the number of eosinophils/1000 cells in the bone marrow of a given untreated mouse cannot be reliably predicted. At a 99% confidence level, the value would lie between 5-139.

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