THE DIURNAL PATTERN OF PLASMA GROWTH HORMONE CONCENTRATION IN CHILDREN AND ADOLESCENTS

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Abstract
SUMMARY: The diurnal pattern of plasma growth hormone levels has been investigated in nine children, without endocrinopathy, aged 8–15 yr., from whom blood samples were taken hourly during the day and 2-hourly at night. Growth hormone was undetectable (< 1 μmg./ml.) during the first 2 hr. after meals but the levels rose thereafter to values many times higher than those found in adults. High values were consistently encountered during the night.