The Tuberous Sclerosis Complex
Top Cited Papers
- 28 September 2006
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 355 (13) , 1345-1356
- https://doi.org/10.1056/nejmra055323
Abstract
The tuberous sclerosis complex (TSC), a multisystem, autosomal dominant disorder affecting children and adults, results from mutations in one of two genes, TSC1 (encoding hamartin) or TSC2 (encoding tuberin). In this article, the current knowledge of the pathogenesis of the disease and its management are discussed.Keywords
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