Abstract
The importance of allergy, or an altered state of reactivity to specific agents, has been stressed repeatedly in the recent ophthalmic literature. Much of this literature deals with purely experimental lesions of the eye, and a small amount deals with clinical investigation. Rather broad deductions appear to have been made from these experimental and clinical findings, and at present clinical ophthalmologists are constantly confronted with the questions of therapeutic desensitization and various forms of vaccine treatment for patients with inflammatory lesions of the conjunctiva and anterior part of the uveal tract. I have no wish to minimize the importance of allergic reactions in these conditions. However, the questions involved are complicated and in many instances not clearly understood, and often lie more in the domain of the immunologist and of the bacteriologist than in the province of the ophthalmologist. It is my purpose in this paper to outline, from

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