Enzymatic Basis of Mannose Toxicity in Honey Bees
- 29 January 1960
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 131 (3396) , 297-298
- https://doi.org/10.1126/science.131.3396.297
Abstract
Honey bees have a negligible amount of phosphomannoseisomerase, together with a high content of a hexokinase which phosphorylates mannose more efficiently than fructose or glucose. Competition at the phosphorylation level plus accumulation of mannose-6-phosphate can fully account for the toxicity of mannose in honey bees.Keywords
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