Involvement of CYP3A1, 2B1, and 2E1 in C-8 hydroxylation and CYP 1A2 and flavin-containing monooxygenase in N-demethylation of caffeine: identified by using inducer treated rat liver microsomes that are characterized with testosterone metabolic patterns
- 1 May 1998
- journal article
- Published by Elsevier in Chemico-Biological Interactions
- Vol. 113 (1) , 1-14
- https://doi.org/10.1016/s0009-2797(97)00109-9
Abstract
No abstract availableKeywords
This publication has 20 references indexed in Scilit:
- Developmental regulation of flavin-containing monooxygenase (FMO) isoforms 1 and 2 in pregnant rabbitPublished by Elsevier ,2000
- Oxidation of Caffeine to Theobromine and Theophylline Is Catalyzed Primarily by Flavin-Containing Monooxygenase in Liver MicrosomesBiochemical and Biophysical Research Communications, 1997
- The Effect of Spironolactone Treatment on the Cytochrome P450-Mediated Metabolism of the Pyrrolizidine Alkaloid Senecionine by Hepatic Microsomes from Rats and Guinea PigsToxicology and Applied Pharmacology, 1994
- Recent Studies on the Structure and Function of Multisubstrate Flavin-Containing MonooxygenasesAnnual Review of Pharmacology and Toxicology, 1993
- The P450 Superfamily: Update on New Sequences, Gene Mapping, Accession Numbers, Early Trivial Names of Enzymes, and NomenclatureDNA and Cell Biology, 1993
- Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed human CYP1A2 and CYP2E1Pharmacogenetics, 1992
- The effect of age on inducibility of various types of rat liver cytochrome P-450Xenobiotica, 1992
- Induction of a high affinity nitrosamine demethylase in rat liver microsomes by acetone and isopropanolChemico-Biological Interactions, 1983
- Testosterone oxidation by rat liver microsomes: Effects of phenobarbital pretreatment and the detection of seven metabolites by HPLCBiochemical and Biophysical Research Communications, 1981
- Microsomal oxidation of thiobenzamide. A photometric assay for the flavin-containing monooxygenaseBiochemical and Biophysical Research Communications, 1981