Sonographic Identification of Second-Trimester Fetuses with Down's Syndrome
- 26 November 1987
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 317 (22) , 1371-1376
- https://doi.org/10.1056/nejm198711263172203
Abstract
Fetuses with Down's syndrome are more likely than normal fetuses to have a thickened nuchal skin fold and relatively short femurs on ultrasound examination in the second trimester. We evaluated these measures in more than 5500 fetuses, including 28 who were later found to have Down's syndrome by means of amniocentesis with cytogenetic analysis. Normal femur length was established as a function of biparietal diameter in 192 of the normal fetuses.This publication has 18 references indexed in Scilit:
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