Serum pepsinogen i in rheumatic diseases. reduced levels in sjögren's syndrome

Abstract
Group I pepsinogens were measured by radioimmunoassay in the sera of 93 patients with rheumatic diseases and 99 controls. Patients with rheumatoid arthritis and systemic lupus erythematosus had levels of pepsinogen I similar to controls, whereas patients with Sjögren's syndrome had levels significantly lower than either controls (PPP2-microglobulin and pepsinogen I (r = −0.46, P<0.05).