Depression of the guinea pig cochlear temperature caused by anesthesia and ventral‐approach ear surgery
- 1 August 1980
- journal article
- research article
- Published by Acoustical Society of America (ASA) in The Journal of the Acoustical Society of America
- Vol. 68 (2) , 489-493
- https://doi.org/10.1121/1.384748
Abstract
A chronic implant of a thermocouple on the round window membrane of the guinea pig cochlea determined the cochlear temperature in awake, anesthetized (dial in urethane, Rompun, ketamine, Xylocane) and surgically dissected animals. The normal cochlear temperature was equal to the core (rectal) temperature of the guinea pig (38.5.degree. C) and exactly tracked changes in core temperature in the intact animal, at least down to the 33.degree. C level tested here. Ventral surgery to expose the cochlea results in a decrease to a low value of 31.degree. C in cochlear temperature because of the removal of tissue mass overlying the auditory bulla. Effective use of a heating pad and blanket cover over the body of the guinea pig will regulate core temperature, but the exposed cochlea will always have a lower value than either the temperature measured rectally or in the orophraynx.This publication has 5 references indexed in Scilit:
- Ototoxicity of aminoglycosides correlated with their action on monomolecular films of polyphosphoinositidesBiochemical Pharmacology, 1980
- Radioactive Labeling of Phospholipids and Proteins by Cochlear Perfusion in the Guinea Pig and the Effect of NeomycinActa Oto-Laryngologica, 1977
- Effects of Perilymphatic Perfusion with Neomycin on the Cochlear Microphonic Potential in the Guinea PigActa Oto-Laryngologica, 1977
- XXVII Intracochlear Temperature and the Cochlear ResponseAnnals of Otology, Rhinology & Laryngology, 1962
- Temperature coefficients of cochlear potentialsAmerican Journal of Physiology-Legacy Content, 1960