Influence of derivatization on the chiral selectivity of cyclodextrins: Alkylated/acylated cyclodextrins and γ‐/δ‐lactones as an example
- 1 September 1991
- journal article
- research article
- Published by Wiley in Journal of Microcolumn Separations
- Vol. 3 (5) , 395-402
- https://doi.org/10.1002/mcs.1220030503
Abstract
Selectively alkylated and acylated cyclodextrin derivatives are suitable stationary phases for capillary GC. To obtain a closer insight into the separation mechanism, an inverse substituted cyclodextrin derivative was synthesized and characterized, and its chiral selectivity was compared with a traditionally substituted and characterized cyclodextrin. The influence of a polar group in the cyclodextrin molecule on the enantioselectivity for γ‐/δ‐lactones is shown with a new, diacylated, cyclodextrin derivative.Keywords
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