Oligomerization of deoxynucleoside-bisphosphate dimers: Template and linkage specificity
- 1 January 1989
- journal article
- conference paper
- Published by Springer Nature in Discover Life
- Vol. 19 (1) , 3-6
- https://doi.org/10.1007/bf01808283
Abstract
Evidence is presented that a poly(U) template selectively favors the oligomerization of the activated, 3′–5′ pyrophosphate-linked dimer pdAppdAp, in comparison with the 3′–3′ and 5′–5′ linked dimers. In the absence of poly(U), the 5′–5′linked dimer is the most reactive, and chains are formed which are more than 60 monomer units in length.Keywords
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