Effects of Feeding Medium Chain Triglycerides to Rats for 13 Weeks
- 1 January 1972
- journal article
- Published by S. Karger AG in Annals of Nutrition and Metabolism
- Vol. 14 (6) , 362-370
- https://doi.org/10.1159/000175402
Abstract
Three-week-old male Wistar rats, when maintained for 13 weeks on diets containing 19.3 wt% even or odd medium chain triglycerides (MCT) admixed with 4.9 wt% sunflowerseed oil (SFO), consumed comparable amounts of food in comparison with rats fed 24.2 wt% SFO. The growth of rats fed even MCT was better than those fed odd MCT but it was comparable to the growth of rats kept on SFO diet. Excretion of ketones in urine during the entire experimental period was observed in both MCT groups but more rats in the odd MCT group had ketonuria, which was probably why the blood alkali reserve in this latter group was lower. The data on total protein and albumin in plasma and glutamine oxaloacetic acid transaminase in urine indicated no metabolic derangement. The hematological data were also within physiological limits in the three groups. The histopathological study of the kidneys and liver of the MCT groups revealed no degenerative changes which might explain an increase in their relative weights. The other organs displayed no abnormalities.Keywords
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