Cyclisation/cleavage of macrocycles by ring-closing metathesis on solid support—conformational studies
- 1 January 1997
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 20,p. 1949-1950
- https://doi.org/10.1039/a704976e
Abstract
Grubbs’ ruthenium metathesis catalyst 1 was used to investigate the catalytic cyclisation/cleavage of tetrapeptide-derived macrocycles from a solid support; the rate dependence on substrate conformation has been studied.Keywords
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