Some Studies in the Distribution of Blood-Borne Foreign Particles, Including Bacteria in the Kidney

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Abstract
India ink in small amounts passes through the kidney circulation, while larger doses result in deposits in the glomerular and tubular capillaries, glomerular endothelial cells and in fixed and wandering tissue cells beneath the pelvic mucosa. Lodgement in the glomerular capillaries usually results in a temporary glomerulitis, but may produce infarction if permanent. A pre-existing hydronephrosis results in marked deposits in the cells of the pelvic sub-mucosa and some particles in the pelvic epithelium. This experimental demonstration harmonizes with the clinical findings in pyelonephritis. The results with bacteria are incomplete and not reported.

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