Metallation of 2(1H)-Quinolinone: Synthesis of 3-Substituted Compounds
- 1 November 1995
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1995 (11) , 1362-1364
- https://doi.org/10.1055/s-1995-4108
Abstract
The ortho-directing effect of the amide function in the regioselective lithiation of 2(1H)-quinolinone has been confirmed. Direct or indirect electrophilic substitution may compete with previous multistep procedures to obtain 3-substituted compounds.Keywords
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