Is there a higher level genetic code that directs evolution?
- 1 September 1984
- journal article
- Published by Springer Nature in Molecular and Cellular Biochemistry
- Vol. 64 (1) , 5-13
- https://doi.org/10.1007/bf00420923
Abstract
Because the genetic code is redundant for most amino acids, different codons can be used in a given position without altering the structure of the protein for which the gene codes. This flexibility permits information encoding structural, and therefore functional, properties of RNA and DNA to be transmitted simultaneously by a protein-coding sequence of DNA. Among the other messages that might be transmitted, it is proposed, is one modulating the evolution of the DNA itself.Keywords
This publication has 120 references indexed in Scilit:
- Close relationship between certain nuclear and mitochondrial intronsJournal of Molecular Biology, 1983
- The deletion in a type of δ0-β0-thalassaemia begins in an inverted AluI repeatNature, 1982
- Mechanics of sequence-dependent stacking of bases in B-DNAJournal of Molecular Biology, 1982
- Molecular drive: a cohesive mode of species evolutionNature, 1982
- Comparative model-building of the mammalian serine proteasesJournal of Molecular Biology, 1981
- Base substitutions, length differences and DNA strand asymmetries in the human Gγ and Aγ fetal globin gene regionCell, 1981
- Gene conversion between duplicated genetic elements in yeastNature, 1981
- Proteins Controlling the Helical Structure of DNAAnnual Review of Biochemistry, 1981
- Studies on the bacteriophage MS2Journal of Molecular Biology, 1976
- The origin of the genetic codeJournal of Molecular Biology, 1968