Stability of heparin solutions

Publisher Website
Google Scholar
Abstract
Heparin injection B.P., adjusted to a pH between 7.0 and 8.0, preserved with 0.15% chlorocresol, is a relatively stable biological product and may be expected to retain its potency for up to 15 years if stored at 4°, over 7 years at room temperature and 6–8 years at 37°. The stability is markedly reduced if the pH of the solution falls below 6.0, so that a rapid and marked loss in potency can be expected if heparin is sterilised in, or mixed for any length of time with, solutions of dextrose, owing to the low pH of these solutions.

This publication has 1 reference indexed in Scilit: