PRE-IRRADIATION CELIOTOMY AND EXTENDED FIELD IRRADIATION FOR INVASIVE CARCINOMA OF CERVIX

  • 1 January 1977
    • journal article
    • research article
    • Vol. 49  (3) , 333-338
Abstract
Epidermoid carcinoma of the cervix was treated in 120 patients by exploratory celiotomy (with semitherapeutic excision of involved lymph nodes) followed by irradiation. The size of the field used for irradiation was determined by the presence and site of lymph node involvement. Of 64 patients, metastatic cancer in pelvic nodes was found in 40, and in common iliac or aortic nodes in 24. Of the 2 groups, 8 and 3 patients, respectively, survived for 2 yr or more. Irradiation to extended fields (using 5500 rads at 850 rads/week) controlled the cancer satisfactorily within the treated area, but the incidence of bowel complications was high. Recurrent carcinoma usually appeared as distant metastases outside the treatment area which suggests that patients with bulky primary lesions and positive nodes already have systemic disease as treatment is started. A safe yet effective dosage level for radiation therapy to extended fields has not yet been established.