Sperm Production Rates, Sperm Physiology and Fertility in Rats Chronically Treated with Sublethal Doses of Aflatoxin B1

Abstract
Rats chronically treated with sublethal doses of aflatoxin B1 suffered severe testicular degeneration and impaired spermatocytogenesis with a concomitant drop in rate and efficiency of sperm production. Although the major part of sperm maturation was disturbed, there was no noticeable reduction in stored sperm viability. A high degree of fertilization occurred. Treatment made the uterine environment less compatible with normal fetal development with smaller litter size and higher embryo mortality.