ALTERATIONS IN RESPONSE TO SOMATIC PAIN ASSOCIATED WITH ANAESTHESIA
Open Access
- 1 May 1973
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 45 (5) , 497-500
- https://doi.org/10.1093/bja/45.5.497
Abstract
An analeptic, a respiratory stimulant, and an opiate antagonist were studied with respect to their effect on experimentally induced somatic pain. The method of tibial pressure algesimetry was used. Naloxone invariably abolished the analgesia produced by both morphine and pethidine. Nikethamide produced a transient reversal of the analgesic state while doxapram had no effect on either morphine or pethidine analgesia.Keywords
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