Nutritional Value of Plant Materials. II. Prevention of Acute Uremia of the Newborn Rat by Vitamin B12
- 1 December 1949
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 72 (3) , 613-616
- https://doi.org/10.3181/00379727-72-17516
Abstract
Rats were maintained from weaning on a 24% protein ration containing a commercial soybean protein and DL- methionine as the only source of amino acids. The ration contained all available vits. except vit. B12 and ascorbic acid. In about 50% of the litters born on this ration, from one to all of the young developed within 36-48 hrs. an acute, fatal uremia in which the concn. of blood urea rose to values ranging from 150 to as high as 300 mg. per 100 ml. This syndrome could be prevented by a single subcut. injn. of 0.05 [mu]g. of vit. B12 (cobine, Merck) into the young shortly after birth.Keywords
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