PENICILLIN IN THE TREATMENT OF CAVERNOUS SINUS THROMBOPHLEBITIS

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Abstract
Until the advent of the sulfonamides cavernous sinus thrombosis or thrombophlebitis, infected with the staphylococcus, was universally fatal, but several instances of recovery under sulfonamide treatments have been reported. We shall report in this paper an instance of cavernous sinus thrombosis, with staphylococcic septicemia, which was successfully treated with penicillin. A detailed anatomic description of the cavernous sinuses and the clinical significance of their tributaries is contained in a paper by Grove.1According to this author, when a thrombophlebitis of the facial vein develops as a result of the injudicious incision of a furuncle of the upper lip, or the extraction of a hair from an infected follicle of the brow or nares, and this thrombophlebitis extends through the angular and ophthalmic veins to the cavernous sinus (the anterior route) the mortality is 100 per cent. Statistical studies, gathered from previous reports, which included cavernous sinus thrombosis as an

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